Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.64 |
| ▸ | GRM5 | P41594 | 13/20 | 0.54 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3833408 | 0.92 | F10 (0.64) | F10GRM5KLKB1 | |
| SCHEMBL3830346 | 0.89 | F10 (0.53) | F10GRM5KLKB1CNR1CNR2 | |
| SCHEMBL3835622 | 0.83 | F10 (0.58) | F10GRM5KLKB1 | |
| SCHEMBL3830318 | 0.82 | F10 (0.65) | F10KLKB1CNR1CNR2 | |
| SCHEMBL8272855 | 0.82 | F10 (0.70) | F10KLKB1 | |
| SCHEMBL14143311 | 0.80 | ABL1 (0.44) | F10HPGD | |
| SCHEMBL3830434 | 0.80 | F10 (0.55) | F10KLKB1CNR1CNR2 | |
| SCHEMBL3830301 | 0.80 | F10 (0.63) | F10GRM5CNR1CNR2HPGD | |
| SCHEMBL3830916 | 0.80 | F10 (0.64) | F10KLKB1 | |
| SCHEMBL3835344 | 0.79 | F10 (0.49) | F10KLKB1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030141-B2 | Inhibitors of factor Xa and other serine proteases involved in the coagulation cascade | WARNER-LAMBERT COMPANY LLC | 2006-04-18 | — | — | US | claimed |