Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.38 |
| ▸ | GPR88 | Q9GZN0 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13075251 | 1.00 | KMT2A (0.40) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL8279021 | 1.00 | KMT2A (0.40) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL8280179 | 0.91 | SIGMAR1 (0.42) | KMT2ASMYD3SIGMAR1HPGDMAPT | |
| SCHEMBL10316135 | 0.85 | SMYD3 (0.39) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL13075362 | 0.85 | SMYD3 (0.39) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL8279479 | 0.85 | SMYD3 (0.39) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL13219667 | 0.84 | SMYD3 (0.38) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL3719801 | 0.83 | SMN1; SMN2 (0.38) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL3729020 | 0.83 | SMN1; SMN2 (0.38) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 | |
| SCHEMBL13201859 | 0.83 | SMYD3 (0.37) | KMT2ASMYD3GPR88SMN1; SMN2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399749-B2 | Substituted prolines as inhibitors of hepatitis C virus NS3 serine protease | SCHERING CORPORATION (US) | 2008-07-15 | — | — | US | disclosed |