Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 12/20 | 0.72 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5641433 | 0.84 | EPHX1 (1.00) | EPHX1RAB9AEPHX2SMN1; SMN2POLB | |
| SCHEMBL6621016 | 0.84 | EPHX1 (0.71) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL22659944 | 0.82 | POLB (0.75) | EPHX1RAB9AEPHX2SMN1; SMN2POLB | |
| SCHEMBL1425082 | 0.81 | EPHX1 (0.72) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL11927282 | 0.81 | EPHX1 (0.63) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL20041102 | 0.81 | EPHX1 (0.72) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL16825746 | 0.81 | EPHX1 (0.72) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL17316255 | 0.81 | EPHX1 (0.59) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 | |
| SCHEMBL14997509 | 0.81 | EPHX1 (0.72) | EPHX1RAB9AEPHX2SMN1; SMN2POLB | |
| SCHEMBL12995588 | 0.81 | EPHX1 (0.63) | EPHX1RAB9AEPHX2SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079945-A2 | ROCK INHIBITORS AND USES THEREOF | UNIVERSITY OF SOUTH FLORIDA (US) | 2008-07-03 | — | — | WO | disclosed |