Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C3AR1 | Q16581 | 15/20 | 0.60 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27793044 | 0.89 | C3AR1 (0.74) | C3AR1 | |
| SCHEMBL4425908 | 0.89 | C3AR1 (0.74) | C3AR1 | |
| SCHEMBL27793143 | 0.85 | C3AR1 (0.53) | C3AR1 | |
| SCHEMBL14090944 | 0.83 | C3AR1 (0.52) | C3AR1 | |
| SCHEMBL4425958 | 0.81 | C3AR1 (0.61) | C3AR1 | |
| SCHEMBL4438794 | 0.79 | C3AR1 (0.76) | C3AR1 | |
| SCHEMBL4986330 | 0.79 | C3AR1 (0.76) | C3AR1 | |
| SCHEMBL8446744 | 0.78 | LNPEP (0.54) | LNPEPANPEPCNR2ERAP2ERAP1 | |
| SCHEMBL27772085 | 0.78 | C3AR1 (0.69) | C3AR1TAS1R3TAS1R1 | |
| SCHEMBL4438829 | 0.78 | C3AR1 (0.52) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008079371-A1 | MODULATORS OF C3A RECEPTOR AND METHODS OF USE THEREOF | ENCYSIVE PHARMACEUTICALS, INC. (US) | 2008-07-03 | — | — | WO | disclosed |