⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1414866 | 1.00 | — | — | |
| SCHEMBL10709217 | 0.83 | TSHR (0.33) | — | |
| SCHEMBL9688501 | 0.79 | LMNA (0.40) | — | |
| SCHEMBL11239393 | 0.78 | — | — | |
| SCHEMBL11239399 | 0.78 | — | — | |
| SCHEMBL7847435 | 0.78 | LMNA (0.46) | — | |
| SCHEMBL9514188 | 0.78 | LMNA (0.46) | — | |
| SCHEMBL7847438 | 0.78 | LMNA (0.46) | — | |
| SCHEMBL11069975 | 0.76 | TDP1 (0.47) | — | |
| SCHEMBL9562087 | 0.76 | TDP1 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1731495-B1 | PROCESS FOR PRODUCING CYCLOPROPANE MONOACETAL DERIVATIVE AND INTERMEDIATE THEREFOR | KURARAY CO (JP) | 2011-03-16 | — | — | EP | disclosed |
| US-7358400-B2 | Process for producing cyclopropane monoacetal derivative and intermediate therefor | KURARAY CO., LTD. (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20070197836-A1 | Method for producing halogenated unsaturated carbonyl compound | KURARAY CO., LTD. (JP) | 2007-08-23 | — | — | US | disclosed |
| US-20070191643-A1 | Process for producing cyclopropane monoacetal derivative and intermediate therefor | Kuraray Co,, Ltd. (JP) | 2007-08-16 | — | — | US | disclosed |
| EP-1731495-A1 | PROCESS FOR PRODUCING CYCLOPROPANE MONOACETAL DERIVATIVE AND INTERMEDIATE THEREFOR | Kuraray Co., Ltd., Kurashiki Plant (JP) | 2006-12-13 | — | — | EP | disclosed |
| EP-1731494-A1 | METHOD FOR PRODUCING HALOGENATED UNSATURATED CARBONYL COMPOUND | Kuraray Co., Ltd., Kurashiki Plant (JP) | 2006-12-13 | — | — | EP | disclosed |