Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14149327 | 0.87 | CNR2 (0.42) | CNR2L3MBTL1TDP1CNR1KDM4E | |
| SCHEMBL14149325 | 0.85 | CNR2 (0.44) | CNR2L3MBTL1TDP1CNR1KDM4E | |
| SCHEMBL14149123 | 0.85 | CNR2 (0.58) | CNR2L3MBTL1TDP1CNR1KDM4E | |
| SCHEMBL14149106 | 0.82 | KDM4E (0.46) | CNR2L3MBTL1CNR1KDM4E | |
| SCHEMBL14149330 | 0.81 | HCRTR1 (0.39) | CNR2TDP1GPBAR1CNR1KDM4E | |
| SCHEMBL14149026 | 0.81 | L3MBTL1 (0.53) | CNR2L3MBTL1TDP1KDM4EMEN1 | |
| SCHEMBL14149117 | 0.81 | GAA (0.46) | CNR2TP53MEN1ALDH1A1KMT2A | |
| SCHEMBL14148971 | 0.80 | RPS6KB1 (0.39) | CNR2CNR1CCNCCDK8 | |
| SCHEMBL14149292 | 0.80 | PREP (0.41) | CNR2CNR1 | |
| SCHEMBL14148881 | 0.80 | RPS6KB1 (0.40) | CNR2TDP1KDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008088744-A1 | DECAHYDROQUINOLINE ANALOGS AS CB2 RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2008-07-24 | — | — | WO | disclosed |