Isonicotinic Acid

Isonicotinic Acid

SCHEMBL1414914

O=C(O)c1ccncc1.O=C(O)c1ccncc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 1.00
TSHR P16473 2/20 0.61
TP53 P04637 1/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
ALDH1A1 P00352 4/20 0.56
DAO P14920 1/20 0.55
CA1 P00915 2/20 0.55
CA2 P00918 2/20 0.55
HCAR2 Q8TDS4 2/20 0.54
CYP1A2 P05177 2/20 0.54
CYP3A4 P08684 2/20 0.54
CYP2D6 P10635 2/20 0.54
CYP2C19 P33261 2/20 0.54
PLOD2 O00469 1/20 0.54
PLOD3 O60568 1/20 0.54
CYP2C9 P11712 1/20 0.54
HPGD P15428 1/20 0.54
PLOD1 Q02809 1/20 0.54
HIF1A Q16665 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isonicotinic Acid SCHEMBL1108 1.00
Isonicotinic Acid SCHEMBL25270920 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25273146 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL15401690 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25222705 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25269381 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25219686 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25271512 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL25261208 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A
Isonicotinic Acid SCHEMBL11870257 0.97 NAPRT (0.94) NAPRTTSHRTP53MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005944-A Antibacterial metal organic framework composite material and preparation method and application thereof 中国科学院赣江创新研究院 2024-05-10 CN claimed
CN-117447962-A Rare earth-based organic framework composite material and preparation method and application thereof 中国科学院赣江创新研究院 2024-01-26 CN claimed
CN-116589691-A Preparation method and application of rare earth-based spherical MOF 中国科学院赣江创新研究院 2023-08-15 CN claimed
US-7183211-B2 Process for chemical mechanical polishing of semiconductor substrate and aqueous dispersion for chemical mechanical polishing JSR CORPORATION (JP) 2007-02-27 US claimed
JP-5133819-A None JP disclosed
CN-118005944-A Antibacterial metal organic framework composite material and preparation method and application thereof 中国科学院赣江创新研究院 2024-05-10 CN disclosed
CN-117447962-A Rare earth-based organic framework composite material and preparation method and application thereof 中国科学院赣江创新研究院 2024-01-26 CN disclosed
CN-116944505-A MOF structure-based composite wave-absorbing material and preparation method and application thereof 中国科学院赣江创新研究院 2023-10-27 CN disclosed
CN-116589691-A Preparation method and application of rare earth-based spherical MOF 中国科学院赣江创新研究院 2023-08-15 CN disclosed
CN-111925357-B Acylhydrazone compound, pharmaceutical composition and application thereof 中国科学院昆明植物研究所 2023-06-06 CN disclosed
EP-3397617-A1 HISTONE DEMETHYLASE INHIBITORS Celgene Quanticel Research, Inc. (US) 2018-11-07 EP disclosed
EP-2294387-B1 LUMINESCENT NANOSTRUCTURED MATERIALS FOR USE IN ELECTROGENERATED CHEMILUMINESCENCE UNIV TEXAS (US) 2017-08-23 EP disclosed
WO-2009137002-A2 LUMINESCENT NANOSTRUCTURED MATERIALS FOR USE IN ELECTROGENERATED CHEMILUMINESCENCE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2009-11-12 WO disclosed
US-20090114277-A1 Production Process of Photoelectrode for Dye-Sensitized Solar Cell, Photoelectrode for Dye-Sensitized Solar Cell and Dye-Sensitized Solar Cell. TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION (JP) 2009-05-07 US disclosed
EP-2006949-A2 METHOD FOR PRODUCING PHOTOELECTRODE FOR DYE-SENSITIZED SOLAR CELL, PHOTOELECTRODE FOR DYE-SENSITIZED SOLAR CELL, AND DYE-SENSITIZED SOLAR CELL Tokyo University of Science, Educational Foundation (JP) 2008-12-24 EP disclosed
EP-0788601-B1 LONG LIFETIME ANISOTROPY (POLARIZATION) PROBES FOR CLINICAL CHEMISTRY, IMMUNOASSAYS, AFFINITY ASSAYS AND BIOMEDICAL RESEARCH LAKOWICZ JOSEPH R (US) 2006-12-27 EP disclosed
EP-1620869-A2 DYE SENSITIZED SOLAR CELL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2006-02-01 EP disclosed
WO-2004097871-A2 DYE SENSITIZED SOLAR CELL ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL) (CH) 2004-11-11 WO disclosed
WO-1998038496-A1 MEASURING ANALYTES WITH METAL-LIGAND COMPLEX PROBES LAKOWICZ JOSEPH R (US) 1998-09-03 WO disclosed
JP-H05133819-A TEMPERATURE SENSOR RIKAGAKU KENKYUSHO 1993-05-28 JP disclosed