Isonicotinic Acid

Isonicotinic Acid

SCHEMBL15401690

O=C(O)c1ccncc1.[CsH]

nearest known ligand 0.94

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAPRT Q6XQN6 2/20 0.94
MEN1 O00255 1/20 0.58
KMT2A Q03164 1/20 0.58
TSHR P16473 2/20 0.58
TP53 P04637 1/20 0.58
ALDH1A1 P00352 4/20 0.54
DAO P14920 1/20 0.52
CA1 P00915 2/20 0.52
CA2 P00918 2/20 0.52
HCAR2 Q8TDS4 2/20 0.52
CYP1A2 P05177 2/20 0.52
CYP3A4 P08684 2/20 0.52
CYP2D6 P10635 2/20 0.52
CYP2C19 P33261 2/20 0.52
PLOD2 O00469 1/20 0.52
PLOD3 O60568 1/20 0.52
CYP2C9 P11712 1/20 0.52
HPGD P15428 1/20 0.52
PLOD1 Q02809 1/20 0.52
HIF1A Q16665 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isonicotinic Acid SCHEMBL1414914 0.97 NAPRT (1.00) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL1108 0.97
Isonicotinic Acid SCHEMBL25269381 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25273146 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25222705 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25270920 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25261208 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25219686 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL25271512 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53
Isonicotinic Acid SCHEMBL11870257 0.94 NAPRT (0.94) NAPRTMEN1KMT2ATSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
CN-103429370-B Composite metal compositions and mixture thereof 住友化学株式会社 2016-08-24 CN disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
CN-103429370-A Metal complex compositions and mixture thereof SUMITOMO CHEMICAL CO 2013-12-04 CN disclosed