Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | EGFR | P00533 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | TTBK1 | Q5TCY1 | 2/20 | 0.47 |
| ▸ | SYK | P43405 | 7/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13889309 | 0.80 | EGFR (0.55) | TSHREGFRBRAFMEN1KMT2A | |
| SCHEMBL23999542 | 0.78 | MAPT (0.56) | CYP3A4TSHREGFRMEN1KMT2A | |
| SCHEMBL1920769 | 0.78 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6SYKBRAF | |
| SCHEMBL1389429 | 0.78 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6SYKBRAF | |
| SCHEMBL30026816 | 0.78 | CYP3A4 (0.86) | CYP3A4TSHRHDAC6SYKBRAF | |
| SCHEMBL3595281 | 0.77 | SYK (0.60) | CYP3A4TSHRHDAC6TTBK1SYK | |
| SCHEMBL11475061 | 0.77 | CYP3A4 (0.70) | CYP3A4TSHREGFRHDAC6TTBK1 | |
| SCHEMBL13302358 | 0.75 | CYP3A4 (0.82) | CYP3A4TSHRHDAC6SYKBRAF | |
| SCHEMBL563902 | 0.75 | CYP3A4 (0.62) | CYP3A4TSHREGFRHDAC6TTBK1 | |
| SCHEMBL17508253 | 0.75 | CYP3A4 (0.62) | CYP3A4TSHREGFRHDAC6TTBK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008091681-A2 | THERAMUTEIN MODULATORS | HOUSEY GERARD M (US) | 2008-07-31 | — | — | WO | disclosed |