Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 20/20 | 0.70 |
| ▸ | ITGA4 | P13612 | 20/20 | 0.70 |
| ▸ | ITGB7 | P26010 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1413178 | 0.92 | ITGB1 (0.84) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413062 | 0.84 | ITGB1 (0.80) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413105 | 0.82 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1415015 | 0.82 | ITGB1 (0.78) | ITGB1ITGA4ITGB7 | |
| SCHEMBL4781133 | 0.81 | ITGB1 (0.83) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413095 | 0.81 | ITGB1 (1.00) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413094 | 0.81 | ITGB1 (0.85) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413091 | 0.81 | ITGB1 (0.87) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413073 | 0.80 | ITGB1 (0.84) | ITGB1ITGA4ITGB7 | |
| SCHEMBL1413048 | 0.79 | ITGB1 (0.98) | ITGB1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1940827-B1 | CARBAMATE COMPOUNDS WHICH INHIBIT LEUKOCYTE ADHESION MEDIATED BY VLA-4 | ELAN PHARM INC (US) | 2011-03-16 | — | — | EP | disclosed |