Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14153545 | 0.88 | GRM5 (0.55) | GRM5 | |
| SCHEMBL15913884 | 0.88 | GRM5 (0.55) | GRM5 | |
| SCHEMBL14153156 | 0.78 | MAP4K4 (0.44) | — | |
| SCHEMBL13388628 | 0.78 | GRM5 (0.65) | GRM5 | |
| SCHEMBL15649650 | 0.76 | GRM5 (0.63) | GRM5CYP1A2 | |
| SCHEMBL14838804 | 0.76 | CYP1A2 (0.67) | CYP1A2 | |
| SCHEMBL14061768 | 0.75 | GRM5 (0.55) | GRM5 | |
| SCHEMBL16465199 | 0.74 | GRM5 (0.52) | GRM5 | |
| SCHEMBL14838727 | 0.73 | GRM5 (0.66) | GRM5CYP1A2 | |
| SCHEMBL13388619 | 0.73 | GRM5 (1.00) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012162635-A1 | METABOTROPIC GLUTAMATE RECEPTORS 5 MODULATORS AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2012-11-29 | — | — | WO | disclosed |