Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 12/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060347 | 0.92 | VDR (0.62) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14154003 | 0.91 | VDR (0.49) | VDR | |
| SCHEMBL14107897 | 0.89 | VDR (0.48) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL12060518 | 0.85 | VDR (0.52) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL12060516 | 0.85 | VDR (0.52) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107899 | 0.84 | VDR (0.44) | VDRHDAC3HDAC2HDAC6 | |
| SCHEMBL14107895 | 0.84 | VDR (0.44) | VDR | |
| SCHEMBL14107902 | 0.84 | VDR (0.44) | VDR | |
| SCHEMBL14959189 | 0.83 | VDR (0.66) | VDR | |
| SCHEMBL14107901 | 0.83 | VDR (0.43) | VDRHDAC3HDAC2HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402688-B2 | 2,2-Di-substituted 1alpha,25-dihydroxy-19-norvitamin D derivative | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-22 | — | — | US | disclosed |