Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.57 |
| ▸ | EGFR | P00533 | 5/20 | 0.54 |
| ▸ | ABL1 | P00519 | 5/20 | 0.54 |
| ▸ | ABL2 | P42684 | 4/20 | 0.54 |
| ▸ | SRC | P12931 | 10/20 | 0.53 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 1/20 | 0.46 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | INSR | P06213 | 1/20 | 0.46 |
| ▸ | NPM1 | P06748 | 1/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.46 |
| ▸ | LYN | P07948 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | IGF1R | P08069 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14154296 | 0.90 | ADK (0.57) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL14470677 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL14470672 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL15241396 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL19276653 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL13092020 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL15225817 | 0.89 | ADORA2A (0.60) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL14154287 | 0.88 | ADK (0.57) | ADKEGFRABL1ABL2SRC | |
| SCHEMBL14154292 | 0.87 | ADK (0.54) | ADK | |
| SCHEMBL14154251 | 0.87 | ADK (0.56) | ADKEGFRABL1ABL2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7405204-B2 | Nucleoside compounds for treating viral infections | GENELABS TECHNOLOGIES, INC. (US) | 2008-07-29 | — | — | US | disclosed |