Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | AGER | Q15109 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MYC | P01106 | 1/20 | 0.34 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20818339 | 0.85 | MEN1 (0.42) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL6109973 | 0.82 | KDM4E (0.50) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| SCHEMBL6115313 | 0.80 | KDM4E (0.52) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| Acetic Acid SCHEMBL16667162 | 0.79 | KDM4E (0.66) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| Benzene SCHEMBL11818131 | 0.78 | KDM4E (0.70) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| SCHEMBL353589 | 0.78 | KDM4E (0.70) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| SCHEMBL17746083 | 0.77 | KDM4E (0.49) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| SCHEMBL2516051 | 0.77 | KDM4E (0.49) | KDM4EMAPTCYP1A2GABRA1GABRB2 | |
| Hydrochloric Acid SCHEMBL17746085 | 0.77 | KDM4E (0.68) | KDM4EMAPTCYP1A2L3MBTL1ALDH1A1 | |
| SCHEMBL25656256 | 0.76 | KDM4E (0.43) | KDM4EMAPTCYP1A2GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008082488-A1 | 4, 5-RING ANNULATED INDOLE DERIVATIVES FOR TREATING OR PREVENTING OF HCV AND RELATED VIRAL INFECTIONS | SCHERING CORPORATION (US) | 2008-07-10 | — | — | WO | disclosed |