SCHEMBL353589

SCHEMBL353589

CCc1cccnc1C(=O)O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.70
MAPT P10636 2/20 0.70
CYP1A2 P05177 1/20 0.70
ALDH1A1 P00352 4/20 0.57
ALOX15 P16050 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
CYP3A4 P08684 1/20 0.57
TSHR P16473 1/20 0.57
BLM P54132 1/20 0.57
AGER Q15109 1/20 0.57
NPSR1 Q6W5P4 1/20 0.57
MYC P01106 1/20 0.50
GAA P10253 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
NAPRT Q6XQN6 3/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
EGLN2 Q96KS0 1/20 0.41
FTO Q9C0B1 1/20 0.41
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL11818131 1.00 KDM4E (0.70) KDM4EMAPTCYP1A2ALDH1A1ALOX15
Hydrochloric Acid SCHEMBL17746085 0.98 KDM4E (0.68) KDM4EMAPTCYP1A2ALDH1A1ALOX15
Acetic Acid SCHEMBL16667162 0.96 KDM4E (0.66) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL10750681 0.90 KDM4E (0.58) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL11820747 0.88 KDM4E (0.57) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL22653038 0.87 KDM4E (0.64) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL27231741 0.86 KDM4E (0.72) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL6115313 0.86 KDM4E (0.52) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL6109973 0.84 KDM4E (0.50) KDM4EMAPTCYP1A2ALDH1A1ALOX15
SCHEMBL990359 0.84 KDM4E (0.70) KDM4EMAPTCYP1A2ALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 706 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4448741-A2 LIPASE FORMULATIONS AND METHODS THEREOF First Wave Biopharma, Inc. (US) 2024-10-23 EP claimed
CN-118525087-A Lipase formulations and methods thereof 第一浪潮生物制药有限公司 2024-08-20 CN claimed
WO-2024119044-A2 ADRULIPASE COMPOSITIONS First Wave BioPharma, Inc. (US) 2024-06-06 WO claimed
CN-116554238-A Preparation method and application of high-purity beta-nicotinamide mononucleotide 广州市英朴司生物科技有限公司 2023-08-08 CN claimed
CN-116437947-A Non-pig formulations and methods thereof 第一浪潮生物制药有限公司 2023-07-14 CN claimed
WO-2023114390-A2 LIPASE FORMULATIONS AND METHODS THEREOF First Wave BioPharma, Inc. (US) 2023-06-22 WO claimed
EP-4167970-A1 NON-PORCINE FORMULATIONS AND METHODS THEREOF First Wave Biopharma, Inc. (US) 2023-04-26 EP claimed
EP-3386634-B1 ION EXCHANGE RESIN FOR PRODUCING BISPHENOL, AND A METHOD FOR PRODUCING BISPHENOL USING SAID ION EXCHANGE RESIN PTT GLOBAL CHEMICAL PUBLIC CO LTD (TH) 2022-08-24 EP claimed
EP-3972569-A1 NANOPARTICLES COMPRISING ENZALUTAMIDE Helm AG (DE) 2022-03-30 EP claimed
WO-2021257843-A1 NON-PORCINE FORMULATIONS AND METHODS THEREOF AZURRX BIOPHARMA, INC. (US) 2021-12-23 WO claimed
EP-1239835-A1 PHARMACEUTICAL COMPOSITIONS PROVIDING ENHANCED DRUG CONCENTRATIONS Pfizer Products Inc. (US) 2002-09-18 EP claimed
US-20020103225-A1 Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors BEND RESEARCH INC. 2002-08-01 US claimed
US-20020006443-A1 Drug in a solubility-improved form with a concentration-enhancing polymer such as hydroxypropyl methyl cellulose acetate succinate; combination improves bioavailability relative to a control of just solubility improved form BEND RESEARCH, INC. 2002-01-17 US claimed
US-20010053791-A1 Glycogen phosphorylase inhibitor BEND RESEARCH, INC. 2001-12-20 US claimed
US-20010053778-A1 Pharmaceutical compositions of glycogen phosphorylase inhibitors BEND RESEARCH, INC. 2001-12-20 US claimed
WO-2001068055-A1 PHARMACEUTICAL COMPOSITIONS OF GLYCOGEN PHOSPHORYLASE INHIBITORS PFIZER PRODUCTS INC. (US) 2001-09-20 WO claimed
WO-2001068092-A2 GLYCOGEN PHOSPHORYLASE INHIBITOR PFIZER PRODUCTS INC. (US) 2001-09-20 WO claimed
WO-2001047495-A1 PHARMACEUTICAL COMPOSITIONS PROVIDING ENHANCED DRUG CONCENTRATIONS PFIZER PRODUCTS INC. (US) 2001-07-05 WO claimed
EP-1027886-A2 Pharmaceutical solid dispersions Pfizer Products Inc. (US) 2000-08-16 EP claimed
EP-0029837-B1 PHOTOTHERMOGRAPHIC STABILIZERS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-04-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020103225-A1 Pharmaceutical compositions of cholesteryl ester transfer protein inhibitors CETP, HDLBP, NPC1L1 KDM4E 2729/4885MAPT 893/4885CYP1A2 2119/4885
US-20010053791-A1 Glycogen phosphorylase inhibitor PYGL, PYGM, GYS2 KDM4E 2522/4885MAPT 712/4885CYP1A2 1793/4885
US-20010053778-A1 Pharmaceutical compositions of glycogen phosphorylase inhibitors PYGL, PYGM, GYS2 KDM4E 2299/4885MAPT 399/4885CYP1A2 1122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.