Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.67 |
| ▸ | CNR1 | P21554 | 9/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14155489 | 0.92 | CNR1 (0.80) | CNR2CNR1CYP2C9GPR55 | |
| SCHEMBL10138898 | 0.90 | CNR1 (0.79) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL14155495 | 0.89 | CNR2 (0.85) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL661771 | 0.89 | CNR2 (0.70) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL14155485 | 0.86 | CNR2 (0.82) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL10171054 | 0.84 | CNR1 (0.64) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL31529039 | 0.83 | CNR1 (0.71) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL5160340 | 0.83 | CNR1 (0.90) | CNR2CNR1CYP1A2CYP2D6MAPT | |
| SCHEMBL31529034 | 0.83 | CNR1 (0.62) | CNR2CNR1KDM4EMEN1CYP1A2 | |
| SCHEMBL31529019 | 0.83 | CNR1 (0.68) | CNR2CNR1KDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008075118-A1 | NOVEL CB1 ANTAGONISTS AND THEIR PREPARATION | RICHTER GEDEON NYRT. (HU) | 2008-06-26 | — | — | WO | disclosed |