SCHEMBL141558

SCHEMBL141558

COc1ccc(C2(c3ccc(OC(=O)c4cccc(C(C)=O)c4)cc3)CCCCC2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 1/20 0.49
▸ NPSR1 Q6W5P4 1/20 0.49
▸ KMT2A Q03164 9/20 0.43
▸ ESR1 P03372 1/20 0.43
▸ ESR2 Q92731 1/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ MEN1 O00255 4/20 0.41
▸ CASP3 P42574 1/20 0.41
▸ SENP8 Q96LD8 1/20 0.41
▸ SENP7 Q9BQF6 1/20 0.41
▸ SENP6 Q9GZR1 1/20 0.41
▸ ALDH1A1 P00352 1/20 0.41
▸ CYP2C9 P11712 3/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ LMNA P02545 3/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ CYP2C19 P33261 2/20 0.41
▸ MAPT P10636 3/20 0.41
▸ KDM4E B2RXH2 2/20 0.40
▸ HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13656590 0.98 NPSR1 (0.47) GAANPSR1KMT2AESR1ESR2
SCHEMBL14007589 0.95 NPSR1 (0.47) GAANPSR1KMT2AESR1ESR2
SCHEMBL13656591 0.94 NPSR1 (0.45) GAANPSR1KMT2AESR1ESR2
SCHEMBL19863731 0.89 KMT2A (0.43) GAANPSR1KMT2AESR1ESR2
SCHEMBL12345968 0.88 KMT2A (0.48) NPSR1KMT2ATDP1ALDH1A1CYP2C9
SCHEMBL2718813 0.86 KMT2A (0.50) GAANPSR1KMT2ATDP1MEN1
SCHEMBL14580087 0.85 LMNA (0.50) GAANPSR1KMT2ATDP1MEN1
SCHEMBL10022910 0.84 KMT2A (0.56) GAANPSR1KMT2AESR1ESR2
SCHEMBL19863504 0.84 KMT2A (0.45) NPSR1KMT2ATDP1ALDH1A1CYP2C9
SCHEMBL12404396 0.84 MAPT (0.46) NPSR1KMT2ATDP1ALDH1A1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9482969-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2016-11-01 — — US disclosed
US-9442400-B2 Electrophotographic photoreceptor including a copolymer polyarylate resin, production method therefor, electrophotographic device including the photoreceptor, and production method for the copolymer polyarylate resin FUJI ELECTRIC CO., LTD. (JP) 2016-09-13 — — US disclosed
US-9201318-B2 Polymer for charge generation layer and charge transport layer formulation XEROX CORPORATION (US) 2015-12-01 — — US disclosed
US-9091949-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-07-28 — — US disclosed
US-9091912-B2 Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2015-07-28 — — US disclosed
US-9075327-B2 Imaging members and methods for making the same XEROX CORPORATION (US) 2015-07-07 — — US disclosed
US-20150177629-A1 IMAGING MEMBERS HAVING ELECTRICALLY AND MECHANICALLY TUNED IMAGING LAYERS XEROX CORPORATION 2015-06-25 — — US disclosed
US-9046798-B2 Imaging members having electrically and mechanically tuned imaging layers XEROX CORPORATION (US) 2015-06-02 — — US disclosed
US-20150086914-A1 IMAGING MEMBERS AND METHODS FOR MAKING THE SAME XEROX CORPORATION (US) 2015-03-26 — — US disclosed
US-8835085-B2 Low strain anti-curl back coating for flexible imaging members XEROX CORPORATION (US) 2014-09-16 — — US disclosed
US-20140087297-A1 LOW STRAIN ANTI-CURL BACK COATING FOR FLEXIBLE IMAGING MEMBERS XEROX CORPORATION (US) 2014-03-27 — — US disclosed
US-20130143016-A1 ALTERNATE ANTICURL BACK COATING FORMULATION XEROX CORPORATION (US) 2013-06-06 — — US disclosed
US-8404414-B2 Electrophotographic photoconductor and manufacturing method thereof FUJI ELECTRIC CO., LTD. (JP) 2013-03-26 — — US disclosed
US-20120058422-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, PROCESS FOR PRODUCING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD (JP) 2012-03-08 — — US disclosed
US-20110189603-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR AND MANUFACTURING METHOD THEREOF FUJI ELECTRIC SYSTEMS CO., LTD. (JP) 2011-08-04 — — US disclosed
US-7901855-B2 Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2011-03-08 — — US disclosed
US-7875410-B2 capable opersistently exerting effect of mitigating contact stress with contact members and improved potential stability during repeated use; polycarbonates CANON KABUSHIKI KAISHA (JP) 2011-01-25 — — US disclosed
US-20100092208-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
US-20100092209-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2010-04-15 — — US disclosed
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