Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12111744 | 0.91 | TSHR (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12285266 | 0.88 | TSHR (0.49) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL2602737 | 0.86 | TSHR (0.53) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL31247953 | 0.85 | TSHR (0.51) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13642707 | 0.84 | THRB (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13642530 | 0.84 | THRB (0.42) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13642527 | 0.83 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL13642353 | 0.83 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12737759 | 0.81 | TSHR (0.36) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL12111747 | 0.81 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170073468-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2017-03-16 | — | — | US | disclosed |
| US-7384990-B2 | Latex particulates with active ester functional groups | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2008-06-10 | — | — | US | disclosed |