Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PTPRB | P23467 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9651601 | 0.91 | ABCB1 (0.38) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| Hydrochloric Acid SCHEMBL9653115 | 0.90 | ABCB1 (0.38) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL22017474 | 0.87 | SMN1; SMN2 (0.46) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL8868383 | 0.86 | CTSK (0.39) | ABCB1PTPRBCTSKCTSSPI4KB | |
| SCHEMBL9652891 | 0.85 | SMN1; SMN2 (0.41) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL7535850 | 0.83 | TSHR (0.47) | SMN1; SMN2GAACYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9076717 | 0.83 | ABCB1 (0.45) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL9074827 | 0.83 | CYP1A2 (0.42) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL9652877 | 0.81 | SMN1; SMN2 (0.37) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 | |
| SCHEMBL9076896 | 0.81 | ABCB1 (0.41) | ABCB1SMN1; SMN2GAAPTPRBCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381734-B2 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2008-06-03 | — | — | US | disclosed |
| US-7157585-B2 | Serine protease inhibitors | TULARIK LIMITED (GB) | 2007-01-02 | — | — | US | disclosed |