Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 14/20 | 0.77 |
| ▸ | ADORA1 | P30542 | 14/20 | 0.77 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4806960 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4806949 | 1.00 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4809340 | 0.99 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4809351 | 0.99 | ADORA3 (0.77) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4803105 | 0.92 | ADORA1 (0.65) | ADORA3ADORA1ADORA2AADORA2B | |
| SCHEMBL14156396 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4798057 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4798107 | 0.90 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL14156290 | 0.89 | ADORA3 (0.76) | ADORA3ADORA1ADORA2AADORA2BMEN1 | |
| SCHEMBL4797947 | 0.89 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AADORA2BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381714-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2008-06-03 | — | — | US | disclosed |
| US-7381714-B2 | A1 adenosine receptor agonists | CV THERAPEUTICS, INC. (US) | 2008-06-03 | — | — | US | disclosed |