SCHEMBL14159119

SCHEMBL14159119

COc1ccc(C)cc1N=Nc1c(N)c(/N=N\c2cc(S(=O)(=O)CCOS(=O)(=O)O)ccc2OC)c(N)c(N=Nc2ccc(SOOCCN)cc2S(=O)(=O)O)c1C(=O)O

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PHLPP2 Q6ZVD8 1/20 0.36
▸ PRMT1 Q99873 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14159108 0.97 PRMT1 (0.34) PHLPP2PRMT1
SCHEMBL14159115 0.89 PHLPP2 (0.41) PHLPP2
SCHEMBL14159104 0.86 THRB (0.38) PHLPP2
SCHEMBL14159106 0.81 THRB (0.39) PHLPP2
SCHEMBL14159120 0.80 PHLPP2 (0.38) PHLPP2
SCHEMBL14159105 0.79 PHLPP2 (0.53) PHLPP2
SCHEMBL14159117 0.78 PHLPP2 (0.52) PHLPP2
SCHEMBL14159098 0.77 THRB (0.36) PHLPP2
SCHEMBL14546780 0.76 PRMT1 (0.42) PHLPP2PRMT1
SCHEMBL14546986 0.75 PRMT1 (0.43) PHLPP2PRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7390889-B1 Trisazo reactive dyestuff compound EVERLIGHT USA, INC. (US) 2008-06-24 — — US disclosed
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