Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | CFD | P00746 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8266911 | 0.85 | CYP4F2 (0.44) | CYP4F2CYP4A11FFAR1FFAR4PDK2 | |
| SCHEMBL7353766 | 0.84 | KMT2A (0.51) | CYP4F2CYP4A11KDM4ERAB9A | |
| SCHEMBL28321278 | 0.83 | ACLY (0.48) | CYP4F2CYP4A11ALDH1A1HPGDNPC1 | |
| Hydrogen Sulfide SCHEMBL28029150 | 0.83 | KMT2A (0.50) | KDM4ERAB9A | |
| SCHEMBL3550978 | 0.81 | FOLH1 (0.50) | KDM4E | |
| SCHEMBL1919862 | 0.79 | DRD1 (0.46) | CYP4F2CYP4A11FFAR1FFAR4KDM4E | |
| SCHEMBL2557632 | 0.79 | EPHX1 (0.43) | CYP4F2CYP4A11KDM4EALDH1A1TSHR | |
| SCHEMBL6163833 | 0.78 | AR (0.44) | HPGD | |
| SCHEMBL14339319 | 0.78 | KMT2A (0.40) | CYP4F2CYP4A11FFAR1FFAR4REN | |
| Benzyl Bromide SCHEMBL28335199 | 0.78 | PTGER1 (0.43) | CYP4F2CYP4A11FFAR1FFAR4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748990-B1 | PROCESS FOR THE PREPARATION OF TELMISARTAN | CIPLA LTD (IN) | 2008-06-25 | — | — | EP | disclosed |