SCHEMBL14159484

SCHEMBL14159484

CCN(CCCl)c1ccc(C=CC2=[N+](C)c3ccccc3C2(C)C)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.58
APP P05067 3/20 0.58
MEN1 O00255 6/20 0.42
KMT2A Q03164 6/20 0.42
LMNA P02545 4/20 0.42
ALDH1A1 P00352 4/20 0.42
HTT P42858 2/20 0.42
THRB P10828 2/20 0.42
RECQL P46063 2/20 0.42
CTDSP1 Q9GZU7 1/20 0.42
VDR P11473 5/20 0.42
MMP14 P50281 1/20 0.41
BCHE P06276 2/20 0.39
ACHE P22303 2/20 0.39
NPC1 O15118 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13235724 0.94 MAPT (0.58) MAPTAPPMEN1KMT2ALMNA
SCHEMBL16253381 0.91 MAPT (0.68) MAPTAPPMEN1KMT2ALMNA
SCHEMBL8995923 0.91 MAPT (0.68) MAPTAPPMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL14674430 0.90 MAPT (0.67) MAPTAPPMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL29429013 0.90 MAPT (0.67) MAPTAPPMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL14675272 0.90 MAPT (0.67) MAPTAPPMEN1KMT2ALMNA
Iodide SCHEMBL29249905 0.90 MAPT (0.70) MAPTAPPMEN1KMT2ALMNA
SCHEMBL13043718 0.86 MAPT (0.57) MAPTAPPMEN1KMT2ALMNA
SCHEMBL13236528 0.86 MAPT (0.55) MAPTAPPMEN1KMT2ALMNA
Hydrochloric Acid SCHEMBL2401411 0.85 MAPT (0.56) MAPTAPPMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7381348-B2 Transformation polarization electromagnetic waves emission for liquid crystals and indicators IR GVON KHAN (RU) 2008-06-03 US disclosed