SCHEMBL8995923

SCHEMBL8995923

CCN(CC)c1ccc(/C=C/C2=[N+](C)c3ccccc3C2(C)C)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.68
APP P05067 3/20 0.68
VDR P11473 5/20 0.47
BCHE P06276 2/20 0.46
ACHE P22303 2/20 0.46
MEN1 O00255 6/20 0.45
KMT2A Q03164 6/20 0.45
LMNA P02545 4/20 0.45
HTT P42858 2/20 0.45
MMP14 P50281 1/20 0.45
ALDH1A1 P00352 5/20 0.44
THRB P10828 2/20 0.44
RECQL P46063 2/20 0.44
CTDSP1 Q9GZU7 1/20 0.44
NPC1 O15118 2/20 0.43
NPSR1 Q6W5P4 2/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2D6 P10635 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16253381 1.00 MAPT (0.68) MAPTAPPVDRBCHEACHE
Hydrochloric Acid SCHEMBL29429013 0.99 MAPT (0.67) MAPTAPPVDRBCHEACHE
Iodide SCHEMBL29249905 0.99 MAPT (0.70) MAPTAPPVDRBCHEACHE
Hydrochloric Acid SCHEMBL14675272 0.99 MAPT (0.67) MAPTAPPVDRBCHEACHE
Hydrochloric Acid SCHEMBL14674430 0.99 MAPT (0.67) MAPTAPPVDRBCHEACHE
SCHEMBL14159484 0.91 MAPT (0.58) MAPTAPPVDRBCHEACHE
SCHEMBL13069889 0.89 MAPT (0.57) MAPTAPPVDRBCHEACHE
SCHEMBL13236528 0.88 MAPT (0.55) MAPTAPPVDRBCHEACHE
SCHEMBL10071789 0.87 MAPT (0.54) MAPTAPPVDRBCHEACHE
SCHEMBL6128356 0.87 MAPT (0.60) MAPTAPPVDRBCHEACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190002717-A1 INK, TEXTILE PRINTING METHOD, PRINTED TEXTILE AND INK AGENT FOR TEXTILE JSR CORPORATION (JP) 2019-01-03 US disclosed
US-9760060-B2 Photopolymer formulations for producing holographic media having highly crosslinked matrix polymers COVESTRO DEUTSCHLAND AG (DE) 2017-09-12 US disclosed
US-9754084-B2 Method for selecting photoinitiator systems COVESTRO DEUTSCHLAND AG (DE) 2017-09-05 US disclosed
US-9504637-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-11-29 US disclosed
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2016-04-21 US disclosed
US-9248086-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2016-02-02 US disclosed
US-9146456-B2 Photopolymer formulation for producing holographic media having highly crosslinked matrix polymers BAYER INTELLECTUAL PROPERTY GMBH (DE) 2015-09-29 US disclosed
US-20150261938-A1 METHOD FOR SELECTING PHOTOINITIATOR SYSTEMS BAYER MATERIALSCIENCE AG (DE) 2015-09-17 US disclosed
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. 2015-06-25 US disclosed
US-8758451-B2 Coloring agents and methods of use thereof LIVING PROOF, INC. (US) 2014-06-24 US disclosed
US-8003589-B2 Laundry composition THE PROCTER & GAMBLE COMPANY (US) 2011-08-23 US disclosed
US-20110189116-A1 HAIR TREATMENT METHODS PERACHEM LIMITED (GB) 2011-08-04 US disclosed
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF LIVING PROOF, INC. (US) 2011-06-30 US disclosed
US-7754863-B2 Metal complex compounds for the optical recording, storage and playback of information; satisfactory sensitivity and recording properties, especially at high recording speeds CIBA SPECIALTY CHEMICALS CORP. (US) 2010-07-13 US disclosed
US-20090186797-A1 LAUNDRY COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2009-07-23 US disclosed
US-20080229519-A1 Liquid treatment composition PROCTER & GAMBLE COMPANY, THE 2008-09-25 US disclosed
US-20070248782-A1 High-Capacity Optical Storage Media CIBA SPECIALTY CHEMICALS CORP. 2007-10-25 US disclosed
WO-2007111887-A2 LAUNDRY COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2007-10-04 WO disclosed
US-7208459-B2 Laundry detergent compositions with efficient hueing dye THE PROCTER & GAMBLE COMPANY (US) 2007-04-24 US disclosed
US-7205269-B2 Laundry detergent compositions with hueing dye THE PROCTER & GAMBLE COMPANY (US) 2007-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110154583-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MAPT 2715/4885APP 3550/4885VDR 3262/4885
US-20160106648-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MAPT 2715/4885APP 3550/4885VDR 3262/4885
US-20110189116-A1 HAIR TREATMENT METHODS TST, POLR1C, NACA MAPT 1499/4885APP 3307/4885VDR 3569/4885
US-20150174026-A1 COLORING AGENTS AND METHODS OF USE THEREOF MPO, HLA-C, ADH7 MAPT 2715/4885APP 3550/4885VDR 3262/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.