Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | FASN | P49327 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159750 | 1.00 | MAOB (0.39) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL14159746 | 1.00 | MAOB (0.39) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL14159890 | 1.00 | MAOB (0.39) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL19798262 | 0.87 | MAOB (0.37) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL18699092 | 0.87 | MAOB (0.40) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL16573167 | 0.87 | MAOB (0.37) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL14159745 | 0.82 | GAA (0.43) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL21850372 | 0.82 | GAA (0.43) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL14159689 | 0.77 | MAOB (0.41) | MAOBDDB1CRBNCTRB1F2 | |
| SCHEMBL18698981 | 0.77 | CA1 (0.40) | CA1CA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |