Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159750 | 0.87 | MAOB (0.39) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL14159784 | 0.87 | MAOB (0.39) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL14159890 | 0.87 | MAOB (0.39) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL14159746 | 0.87 | MAOB (0.39) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL16573167 | 0.85 | MAOB (0.37) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL21850372 | 0.80 | GAA (0.43) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL14159745 | 0.80 | GAA (0.43) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL19798262 | 0.80 | MAOB (0.37) | MAOBDDB1CRBNF2PRSS1 | |
| SCHEMBL21022868 | 0.76 | — | — | |
| SCHEMBL14159689 | 0.75 | MAOB (0.41) | MAOBDDB1CRBNF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3150595-A1 | DERIVATIVES OF UK-2A | DOW AGROSCIENCES LLC (US) | 2017-04-05 | — | — | EP | disclosed |