Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409642 | 1.00 | POLB (0.35) | POLBGABRA1GABRA5CA1CA2 | |
| SCHEMBL3813245 | 0.94 | CA1 (0.39) | POLBCA1CA2CA4KMT2A | |
| SCHEMBL27053573 | 0.87 | POLB (0.37) | POLBKMT2AL3MBTL1APEX1RECQL | |
| SCHEMBL14284261 | 0.86 | ALDH1A1 (0.39) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL30288169 | 0.86 | ALDH1A1 (0.39) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL30879564 | 0.86 | ALDH1A1 (0.39) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL30288152 | 0.86 | ALDH1A1 (0.39) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL2038990 | 0.86 | ALDH1A1 (0.39) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL4951220 | 0.72 | ALDH1A1 (0.42) | POLBKMT2AL3MBTL1RECQLTDP1 | |
| SCHEMBL27711787 | 0.70 | CA1 (0.42) | GABRA1GABRA5CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1516874-B1 | Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation | DOW AGROSCIENCES LLC (US) | 2015-08-19 | — | — | EP | disclosed |
| EP-1204643-B1 | FUNGICIDAL HETEROCYCLIC AROMATIC AMIDES AND THEIR COMPOSITIONS, METHODS OF USE AND PREPARATION | DOW AGROSCIENCES LLC (US) | 2008-06-04 | — | — | EP | disclosed |