Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14159927 | 0.94 | POLB (0.46) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14159933 | 0.91 | MAPT (0.37) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14094980 | 0.86 | CA12 (0.39) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14159940 | 0.85 | MAPT (0.39) | POLBMAPTNPC1HTTAPP | |
| SCHEMBL14159930 | 0.80 | POLB (0.46) | CA12CA1CA2CA9POLB | |
| SCHEMBL14094971 | 0.79 | MAPT (0.47) | NFKB1POLBMAPTNPC1HTT | |
| SCHEMBL14159926 | 0.77 | CA12 (0.46) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14159929 | 0.76 | POLB (0.47) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL14159931 | 0.76 | HSD17B10 (0.37) | NFKB1CA12CA1CA2CA9 | |
| SCHEMBL2205292 | 0.75 | SENP2 (0.43) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7381256-B2 | Mixtures of fiber-reactive azo dyes, their production and their use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2008-06-03 | — | — | US | disclosed |
| US-20070209540-A1 | Mixtures Of Fiber-Reactive Azo Dyes, Their Production And Their Use | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2007-09-13 | — | — | US | disclosed |