SENP2

Sentrin-specific protease 2 · Q9HC62 · SENP2 on Sugi Atlas →

13,547 patent compounds predicted against SENP2, 7,552 high-confidence (nearest known ligand ≥ 0.5)

Top predicted compounds (top 20 by supporting neighbours, then confidence)

CompoundConfidenceSupporting neighbours
SCHEMBL485085 SCHEMBL485085 0.58 19/20
SCHEMBL485651 SCHEMBL485651 0.57 19/20
SCHEMBL485276 SCHEMBL485276 0.46 19/20
SCHEMBL485260 SCHEMBL485260 0.56 18/20
SCHEMBL485298 SCHEMBL485298 0.56 18/20
SCHEMBL484955 SCHEMBL484955 0.47 18/20
SCHEMBL485732 SCHEMBL485732 0.46 18/20
SCHEMBL485458 SCHEMBL485458 0.59 17/20
SCHEMBL485661 SCHEMBL485661 0.47 17/20
SCHEMBL1000592 SCHEMBL1000592 0.50 16/20
SCHEMBL1230808 SCHEMBL1230808 0.50 14/20
SCHEMBL1712890 SCHEMBL1712890 0.58 10/20
SCHEMBL1382397 SCHEMBL1382397 0.47 10/20
SCHEMBL110923 SCHEMBL110923 0.60 7/20
SCHEMBL110924 SCHEMBL110924 0.60 7/20
SCHEMBL1436156 SCHEMBL1436156 0.60 7/20
SCHEMBL1436155 SCHEMBL1436155 0.59 7/20
SCHEMBL414245 SCHEMBL414245 0.52 7/20
SCHEMBL1000593 SCHEMBL1000593 0.49 7/20
SCHEMBL2541489 SCHEMBL2541489 0.57 6/20

Clinical trials — most relevant to SENP2 by text similarity (a relevance ranking, not an exhaustive list)

TrialPhaseStatus
A Study of Hydroxychloroquine in Combination With Gemcitabine/Abraxane in Pancreatic Cancer PHASE1/PHASE2COMPLETED
Value of Using Pioglitazone in Chronic Myeloid Leukemia Treatment PHASE2COMPLETED
Pappalysin 2 (PAPP-A2) Enzyme Replacement PHASE1COMPLETED
Inhibition of SENP1 for the Suppression of OS Growth and Metastasis nanUNKNOWN
Evaluation of Prognostic Factors: From Breast Cancer to Bone Metastases nanUNKNOWN
Differential Gene Expression of Liver Tissue and Blood From Individuals With Chronic Viral Hepatitis nanUNKNOWN
Biomarkers in Tumor Samples From Younger Patients With Neuroblastoma nanCOMPLETED
Genetic Mechanisms of Chronic Obstructive Pulmonary Disease (COPD) nanCOMPLETED
Autophagy Bladder Cancer nanUNKNOWN
Apoptosis Markers in Aggressive Periodontitis nanCOMPLETED
Identification of a New Blood Biomarker for the Diagnosis and Prognosis of Liposarcomas nanRECRUITING
Genetic Characterization of Parkinson's Disease nanCOMPLETED
Genetics of Endocrine Tumours - Familial Isolated Pituitary Adenoma - FIPA nanRECRUITING
Genetic Basis of Mitral Valve Prolapse nanUNKNOWN
Identification of an Asthma Susceptibility Gene on 3P nanCOMPLETED
Genetic Basis of Abdominal Aortic Aneurysm nanCOMPLETED
Integrated Proteomic HPLC-ESI-MS Analysis of Salivary Peptides of Preterm Newborns: a Pilot Study nanCOMPLETED
Genetic Determinants of Sudden Cardiac Death nanCOMPLETED
Clinical and Genetic Study of Autism Spectrum Disorder nanCOMPLETED
The Surem TRAF3IP2 Level and Atherosclerotic Plaque Development in Human nanUNKNOWN
PCD New Gene Discovery nanCOMPLETED
Epidemiological and Genetic Studies of Body Mass Index nanCOMPLETED
The Genetic Characterization of Dementia nanCOMPLETED
Role of Genetics in Idiopathic Pulmonary Fibrosis (IPF) nanUNKNOWN
Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia nanUNKNOWN
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS nanCOMPLETED
Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma nanUNKNOWN
Progression Follow up of the First-degree Relatives of Patients With REM Sleep Behavior Disorder nanUNKNOWN
Identification of New FTLD Genes nanUNKNOWN
Family Blood Pressure Program - GenNet Network nanCOMPLETED

Related proteins — ESM-2 sequence neighbours (a SENP2 binder may also engage these)

ProteinNameSimilarity
Q5R7K7 1.000 Q5R7K7 →
Q91ZX6 1.000 Q91ZX6 →
Q9EQE1 0.997 Q9EQE1 →
P59110 0.997 P59110 →
P10244 0.995 P10244 →
Q9FT70 0.995 Q9FT70 →
Q9SB51 0.995 Q9SB51 →
Q9NYI0 0.995 Q9NYI0 →
SENP1 Sentrin-specific protease 1 0.994 landscape →
Q6KAQ7 0.994 Q6KAQ7 →
Q8BZ21 0.994 Q8BZ21 →
A5D979 0.994 A5D979 →
KMT5B Histone-lysine N-methyltransferase KMT5B 0.993 landscape →
Q62661 0.993 Q62661 →
Q6NTJ3 0.992 Q6NTJ3 →
A7E379 0.992 A7E379 →
P0C2N5 0.992 P0C2N5 →
E9Q555 0.992 E9Q555 →
Q9FY74 0.992 Q9FY74 →
BLM RecQ-like DNA helicase BLM 0.992 landscape →
Q9Z1J2 0.992 Q9Z1J2 →
Q5R978 0.992 Q5R978 →
O70445 0.992 O70445 →
Q8WML3 0.992 Q8WML3 →
Q9JIC3 0.992 Q9JIC3 →
Q8JZS6 0.992 Q8JZS6 →
Q5RJX8 0.992 Q5RJX8 →
Q9Z2U2 0.992 Q9Z2U2 →
MAP3K13 Mitogen-activated protein kinase kinase kinase 13 0.992 landscape →
Q6A037 0.992 Q6A037 →