Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MGAM | O43451 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14806709 | 0.81 | KMT2A (0.60) | ALDH1A1ALOX15HPGDHSD17B10MEN1 | |
| SCHEMBL4791247 | 0.77 | NPC1 (0.53) | ALDH1A1ALOX15HPGDHSD17B10MEN1 | |
| SCHEMBL15610685 | 0.77 | KDM4E (0.54) | ALDH1A1ALOX15HPGDHSD17B10MEN1 | |
| SCHEMBL2801533 | 0.75 | NPC1 (0.58) | ALDH1A1ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL30372045 | 0.75 | NPC1 (0.58) | ALDH1A1ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL9318696 | 0.74 | ALOX15 (0.58) | ALDH1A1ALOX15HPGDHSD17B10MGAM | |
| SCHEMBL11617994 | 0.73 | ALOX15 (0.62) | ALDH1A1ALOX15HPGDHSD17B10MEN1 | |
| SCHEMBL30899548 | 0.73 | ALOX15 (0.62) | ALDH1A1ALOX15HPGDHSD17B10MEN1 | |
| SCHEMBL29350099 | 0.73 | NPC1 (0.65) | ALDH1A1ALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL150476 | 0.73 | NPC1 (0.65) | ALDH1A1ALOX15HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1721898-B1 | Quinoline and pyridoquinoxaline derivatives as antibacterial agents | UNIV JORDAN (JO) | 2011-03-16 | — | — | EP | disclosed |
| EP-1721898-A1 | Quinoline and pyridoquinoxaline derivatives as antibacterial agents | University of Jordan (JO) | 2006-11-15 | — | — | EP | disclosed |
| EP-1721898-A1 | Quinoline and pyridoquinoxaline derivatives as antibacterial agents | University of Jordan (JO) | 2006-11-15 | — | — | EP | disclosed |