Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PNP | P00491 | 2/20 | 0.56 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | THPO | P40225 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | EIF4E | P06730 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13320530 | 1.00 | LMNA (0.56) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13320552 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13320568 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL9780439 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13352081 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13351996 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL2841617 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13320653 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL13320587 | 0.84 | LMNA (0.59) | LMNASMN1; SMN2PNPADORA1ALDH1A1 | |
| SCHEMBL3463215 | 0.79 | LMNA (0.63) | LMNASMN1; SMN2PNPADORA1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008067002-A2 | AZOLE NUCLEOSIDES AND USE AS INHIBITORS OF RNA AND DNA VARIAL POLYMERASES | SOUTHERN RESEARCH INSTITUTE (US) | 2008-06-05 | — | — | WO | disclosed |