SCHEMBL14162011

SCHEMBL14162011

C=C(c1ccc(C)c(NC(=O)NCC(C)(C)N)c1)N1CCC(c2ccc(C#N)cc2)CC1

nearest known ligand 0.51

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FASN P49327 20/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4199675 0.92 FASN (0.60) FASN
SCHEMBL14162179 0.87 FASN (0.55) FASN
SCHEMBL14162094 0.87 FASN (0.49) FASN
SCHEMBL14162034 0.87 FASN (0.53) FASN
SCHEMBL14162262 0.85 FASN (0.53) FASN
SCHEMBL14162086 0.85 FASN (0.51) FASN
SCHEMBL14162017 0.85 FASN (0.56) FASN
SCHEMBL14162058 0.85 FASN (0.51) FASN
SCHEMBL4196810 0.84 FASN (0.62) FASN
SCHEMBL14162012 0.84 FASN (0.60) FASN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008075064-A1 PIPERIDINE DERIVATIVES FOR THE TREATMENT OF OBESITY ASTRAZENECA AB (SE) 2008-06-26 WO disclosed