Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | POLQ | O75417 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17329111 | 0.80 | IDO1 (0.59) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL3647884 | 0.80 | IDO1 (0.59) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL2097721 | 0.78 | IDO1 (0.57) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL29389277 | 0.78 | IDO1 (0.57) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL4527 | 0.78 | IDO1 (0.57) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL44837 | 0.78 | IDO1 (0.57) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL29427013 | 0.78 | IDO1 (0.57) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL23337251 | 0.76 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMPOLB | |
| SCHEMBL6835374 | 0.76 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMPOLB | |
| Bromide SCHEMBL581589 | 0.76 | IDO1 (0.55) | IDO1ALDH1A1KDM4EATMPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008077089-A1 | PYRROLIDINANILINES | SMITHKLINE BEECHAM CORPORATION (US) | 2008-06-26 | — | — | WO | disclosed |