SCHEMBL4527

SCHEMBL4527

FC(F)(F)c1ccccc1CBr

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.57
ALDH1A1 P00352 3/20 0.47
KDM4E B2RXH2 2/20 0.47
ATM Q13315 1/20 0.47
POLB P06746 2/20 0.45
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
KMT2A Q03164 1/20 0.44
MAOB P27338 3/20 0.43
POLQ O75417 1/20 0.43
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
DAO P14920 1/20 0.42
AR P10275 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29427013 1.00 IDO1 (0.57) IDO1ALDH1A1KDM4EATMPOLB
SCHEMBL376588 0.86 IDO1 (0.46) IDO1ALDH1A1KDM4EATMTDP1
SCHEMBL9568206 0.84 IDO1 (0.44) IDO1ALDH1A1KDM4EATMTDP1
SCHEMBL30252413 0.84 IDO1 (0.52) IDO1ALDH1A1KDM4EATMPOLB
SCHEMBL3126891 0.84 IDO1 (0.52) IDO1ALDH1A1KDM4EATMPOLB
SCHEMBL5359365 0.84 IDO1 (0.42) IDO1ALDH1A1KDM4EATMPOLB
Ammonia Solution, Strong SCHEMBL27704287 0.82 IDO1 (0.50) IDO1ALDH1A1KDM4EATMPOLB
SCHEMBL841044 0.82 AKR1B1 (0.42) IDO1ALDH1A1POLBTDP1L3MBTL1
SCHEMBL144963 0.82 IDO1 (0.41) IDO1ALDH1A1KDM4EATMPOLB
SCHEMBL30806616 0.82 AKR1B1 (0.42) IDO1ALDH1A1POLBTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101052-A Matrine-triazole derivative and synthesis method thereof 吉林医药学院 2024-12-10 CN claimed
CN-107089913-B 2-substituted methyl rupestonic acid derivative and preparation method and application thereof 中国科学院新疆理化技术研究所 2020-10-09 CN claimed
CN-109810568-A Inorganic nano material prints ink and its preparation method and application TCL集团股份有限公司 2019-05-28 CN claimed
CN-109761911-A A kind of preparation method of the polysubstituted pyrimidine derivative as Elagolix intermediate 安徽诺全药业有限公司 2019-05-17 CN claimed
EP-2145895-B1 Process for the manufacturing of glycochips COMMISSARIAT ENERGIE ATOMIQUE (FR) 2013-10-30 EP claimed
US-20100035353-A1 PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 2010-02-11 US claimed
EP-2145895-A1 Process for the manufacturing of glycochips Commissariat à l'Energie Atomique (FR) 2010-01-20 EP claimed
WO-2026107371-A2 INDOLYL-PYRIDINONES AND RELATED COMPOUNDS AND THEIR USE IN THERAPY HOTSPOT THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
US-12624041-B2 Heterocyclic compound and use thereof WUHAN LL SCIENCE AND TECHNOLOGY DEVELOPMENT CO., LTD. (CN) 2026-05-12 US disclosed
US-12612361-B2 Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding NORTHWESTERN UNIVERSITY (US) 2026-04-28 US disclosed
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF SIRONAX LTD (KY) 2026-03-19 US disclosed
US-12559490-B2 Compositions and methods for modulating hair growth THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-24 US disclosed
US-12527774-B2 Estrogen-related receptor alpha modulators LEAD PHARMA HOLDING B.V. (NL) 2026-01-20 US disclosed
US-4754050-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1988-06-28 US disclosed
US-4695573-A COGNITION ACTIVATORS HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1987-09-22 US disclosed
EP-0179383-A2 9-Amino-1,2,3,4-tetrahydroacridin-1-ol and related compounds, a process for their preparation and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1986-04-30 EP disclosed
US-4579582-A REDUCES THE GERMINATION OR EARLY GROWTH OF GRASSES CHEVRON RESEARCH COMPANY (US) 1986-04-01 US disclosed
US-4429119-A PLANT GROWTH REGULATORS CHEVRON RESEARCH COMPANY (US) 1984-01-31 US disclosed
US-4209621-A TRANQUILIZERS AMERICAN CYANAMID COMPANY (US) 1980-06-24 US disclosed
US-4077982-A HERBICIDES FMC CORPORATION (US) 1978-03-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260078130-A1 NAMPT MODULATORS, PREPARATIONS, AND USES THEREOF NAMPT, NNMT, SARM1 IDO1 3108/4885ALDH1A1 2719/4885KDM4E 3382/4885
US-12527774-B2 Estrogen-related receptor alpha modulators ESR2, ESRRA, ESRRB IDO1 4538/4885ALDH1A1 696/4885KDM4E 350/4885
US-12624041-B2 Heterocyclic compound and use thereof TRPC1, TRPC5, TRPC3 IDO1 137/4885ALDH1A1 1028/4885KDM4E 4648/4885
US-20100035353-A1 PROCESS FOR THE MANUFACTURING OF GLYCOCHIPS HGF, HGFAC, HDGF IDO1 4161/4885ALDH1A1 2043/4885KDM4E 3944/4885
US-12559490-B2 Compositions and methods for modulating hair growth PC, MTCH2, MPC2 IDO1 645/4885ALDH1A1 605/4885KDM4E 836/4885
US-12612361-B2 Substituted pyrrolidones and piperidones as small molecule inhibitors of EZH2 and EED protein binding EED, EZH2, EZH1 IDO1 2321/4885ALDH1A1 1322/4885KDM4E 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.