Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL28525357 | 1.00 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| Potassium Ion SCHEMBL132447 | 1.00 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| Potassium Ion SCHEMBL28218945 | 0.97 | HTR6 (0.52) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL17942459 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL20533805 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL6916781 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL20583771 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL20533807 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL8374927 | 0.94 | CA1 (0.57) | HTR6CA1CA2ALDH1A1CA12 | |
| SCHEMBL8622107 | 0.94 | HTR6 (0.55) | HTR6CA1CA2ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2524946-B1 | POLYCARBONATE RESIN COMPOSITION | TEIJIN CHEMICALS LTD (JP) | 2016-05-04 | — | — | EP | disclosed |
| US-8648165-B2 | Polycarbonate resin composition | TEIJIN CHEMICALS, LTD. (JP) | 2014-02-11 | — | — | US | disclosed |
| EP-2524946-A1 | POLYCARBONATE RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120289655-A1 | POLYCARBONATE RESIN COMPOSITION | TEIJIN CHEMICALS, LTD. (JP) | 2012-11-15 | — | — | US | disclosed |
| US-20120148819-A1 | RESIN COMPOSITION AND FLAT PANEL DISPLAY FIXING FRAME | NAKAGAWA HIDENORI (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20110195222-A1 | RESIN COMPOSITION AND FLAT PANEL DISPLAY FIXING FRAME | NAKAGAWA HIDENORI | 2011-08-11 | — | — | US | disclosed |
| US-7939591-B2 | Polycarbonate resin composition | TEIJIN CHEMICALS, LTD. (JP) | 2011-05-10 | — | — | US | disclosed |
| EP-1882718-B1 | POLYCARBONATE RESIN COMPOSITION | TEIJIN CHEMICALS LTD (JP) | 2011-03-16 | — | — | EP | disclosed |
| EP-1808462-B1 | RESIN COMPOSITION AND FIXING FRAMES FOR FLAT-PANEL DISPLAYS | TEIJIN CHEMICALS LTD (JP) | 2009-11-25 | — | — | EP | disclosed |
| US-20090118406-A1 | Polycarbonate resin composition | TEIJIN CHEMICALS LTD. (JP) | 2009-05-07 | — | — | US | disclosed |
| EP-1882718-A1 | POLYCARBONATE RESIN COMPOSITION | Teijin Chemicals, Ltd. (JP) | 2008-01-30 | — | — | EP | disclosed |
| US-20070257401-A1 | Resin Composition and Flat Panel Display Fixing Frame | TEIJIN CHEMICALS LTD. (JP) | 2007-11-08 | — | — | US | disclosed |
| EP-1808462-A1 | RESIN COMPOSITION AND FIXING FRAMES FOR FLAT-PANEL DISPLAYS | Teijin Chemicals, Ltd. (JP) | 2007-07-18 | — | — | EP | disclosed |
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |
| US-20050131105-A1 | Filler reinforced polyether imide resin composition and molded article thereof | SHPP GLOBAL TECHNOLOGIES B.V. (NL) | 2005-06-16 | — | — | US | disclosed |