SCHEMBL1416280

SCHEMBL1416280

O=C(NCCOCCOCCO)Oc1[c]cccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.43
LMNA P02545 2/20 0.43
ALDH1A1 P00352 3/20 0.35
RAB9A P51151 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
TLR2 O60603 1/20 0.34
TLR1 Q15399 1/20 0.34
KCNH3 Q9ULD8 1/20 0.34
KDM4E B2RXH2 1/20 0.34
NCEH1 Q6PIU2 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
TAAR1 Q96RJ0 2/20 0.32
NPC1 O15118 1/20 0.32
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
ACHE P22303 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416073 0.99 SMN1; SMN2 (0.44) SMN1; SMN2LMNAALDH1A1RAB9AL3MBTL1
SCHEMBL1416012 0.88 SMN1; SMN2 (0.43) SMN1; SMN2LMNAALDH1A1RAB9AKDM4E
SCHEMBL1416480 0.86 SMN1; SMN2 (0.44) SMN1; SMN2ALDH1A1RAB9AKDM4EMEN1
SCHEMBL1416764 0.85 SMN1; SMN2 (0.41) SMN1; SMN2LMNAALDH1A1L3MBTL1KDM4E
SCHEMBL1416274 0.85 SMN1; SMN2 (0.46) SMN1; SMN2LMNAALDH1A1RAB9AL3MBTL1
SCHEMBL1416259 0.83 SMN1; SMN2 (0.47) SMN1; SMN2LMNAALDH1A1RAB9AL3MBTL1
SCHEMBL1416201 0.83 HTT (0.39) SMN1; SMN2ALDH1A1KDM4ENCEH1HTT
SCHEMBL1416205 0.82 HPGD (0.46) SMN1; SMN2ALDH1A1RAB9AL3MBTL1KDM4E
SCHEMBL1416283 0.76 SMN1; SMN2 (0.44) SMN1; SMN2LMNARAB9ATAAR1NPC1
SCHEMBL25247 0.75 KMT2A (0.44) SMN1; SMN2LMNARAB9AL3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed