SCHEMBL1416764

SCHEMBL1416764

CCOCCNC(=O)Oc1[c]cccc1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.41
LMNA P02545 1/20 0.41
ASAH1 Q13510 1/20 0.39
HPGD P15428 3/20 0.39
HTT P42858 1/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
NCEH1 Q6PIU2 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
NAMPT P43490 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416012 0.97 SMN1; SMN2 (0.43) SMN1; SMN2LMNAASAH1HPGDHTT
SCHEMBL1416073 0.86 SMN1; SMN2 (0.44) SMN1; SMN2LMNAHTTNPC1NCEH1
SCHEMBL1416205 0.86 HPGD (0.46) SMN1; SMN2HPGDKMT2AMEN1NPC1
SCHEMBL1416280 0.85 SMN1; SMN2 (0.43) SMN1; SMN2LMNAHTTKMT2AMEN1
SCHEMBL1416092 0.84 SMN1; SMN2 (0.44) SMN1; SMN2LMNAASAH1HPGDHTT
SCHEMBL25247 0.82 KMT2A (0.44) SMN1; SMN2LMNAKMT2AMEN1NPC1
SCHEMBL7469147 0.82 MGLL (0.51)
SCHEMBL1416480 0.81 SMN1; SMN2 (0.44) SMN1; SMN2HTTKMT2AMEN1NPC1
SCHEMBL1416201 0.78 HTT (0.39) SMN1; SMN2HTTNCEH1KDM4EALDH1A1
SCHEMBL5108042 0.78 TAAR1 (0.52) SMN1; SMN2LMNANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed