Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 19/20 | 0.87 |
| ▸ | CA1 | P00915 | 17/20 | 0.87 |
| ▸ | CA2 | P00918 | 17/20 | 0.87 |
| ▸ | CA12 | O43570 | 8/20 | 0.76 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.76 |
| ▸ | CA7 | P43166 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14163754 | 0.93 | CA9 (1.00) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163766 | 0.92 | CA9 (0.88) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163775 | 0.92 | CA9 (0.89) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163769 | 0.91 | CA9 (0.86) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163772 | 0.91 | CA9 (0.86) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163765 | 0.91 | CA9 (0.86) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163768 | 0.90 | CA9 (0.86) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163767 | 0.90 | CA9 (0.86) | CA9CA1CA2CA12CA14 | |
| SCHEMBL13263774 | 0.90 | CA9 (1.00) | CA9CA1CA2CA12CA14 | |
| SCHEMBL14163755 | 0.89 | CA9 (0.89) | CA9CA1CA2CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080138291-A1 | Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents | UNION LIFE SCIENCES LTD. (GB) | 2008-06-12 | — | — | US | disclosed |
| US-20080138291-A1 | Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents | UNION LIFE SCIENCES LTD. (GB) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080138291-A1 | Sulfonamide Derivatives Having Carbonic Anhydrase Inhibiting Activity and their Use as Therapeutic and Diagnostic Agents | CA9, CA4, CA2 | CA9 1/4885CA1 8/4885CA2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.