Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.86 |
| ▸ | ADRB2 | P07550 | 19/20 | 0.86 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166151 | 1.00 | CHRM3 (0.86) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14695269 | 0.94 | ADRB2 (0.98) | CHRM3ADRB2 | |
| SCHEMBL14695274 | 0.94 | ADRB2 (0.98) | CHRM3ADRB2 | |
| SCHEMBL14695278 | 0.94 | ADRB2 (0.98) | CHRM3ADRB2 | |
| SCHEMBL14694758 | 0.93 | CHRM3 (0.82) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14694759 | 0.93 | CHRM3 (0.82) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14694761 | 0.93 | CHRM3 (0.82) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14694757 | 0.93 | CHRM3 (0.82) | CHRM3ADRB2CACNA1C | |
| SCHEMBL14241225 | 0.93 | ADRB2 (1.00) | CHRM3ADRB2 | |
| SCHEMBL14694469 | 0.93 | ADRB2 (1.00) | CHRM3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | claimed |
| EP-2718280-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2014-04-16 | — | — | EP | claimed |
| WO-2012168359-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-12-13 | — | — | WO | claimed |