Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.41 |
| ▸ | CYSLTR1 | Q9Y271 | 3/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166070 | 0.84 | MEN1 (0.47) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL20373667 | 0.83 | ALOX15 (0.53) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15775507 | 0.81 | MEN1 (0.50) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15775508 | 0.81 | MEN1 (0.50) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL14166023 | 0.80 | SIRT2 (0.51) | KMT2AMEN1TAAR1ALDH1A1LMNA | |
| SCHEMBL14166237 | 0.80 | MEN1 (0.44) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL17074623 | 0.80 | MEN1 (0.44) | KMT2AMEN1TAAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL15777839 | 0.77 | SMPD1 (0.55) | KMT2AMEN1ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL19984429 | 0.77 | CHRM3 (0.62) | KMT2AMEN1SMN1; SMN2TSHR | |
| SCHEMBL20373866 | 0.77 | CHRM3 (0.62) | KMT2AMEN1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-B1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMA SPA (IT) | 2015-09-16 | — | — | EP | disclosed |
| EP-2718280-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168359-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-12-13 | — | — | WO | disclosed |