SCHEMBL1416624

SCHEMBL1416624

CCCCC[CH]OC(=O)NC(C)C

nearest known ligand 0.55

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 3/20 0.46
MEN1 O00255 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
EPHX1 P07099 2/20 0.43
ASAH2 Q9NR71 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KCNK3 O14649 1/20 0.38
ALDH1A1 P00352 1/20 0.38
THRB P10828 1/20 0.38
CNR2 P34972 1/20 0.38
BLM P54132 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
SLC6A5 Q9Y345 1/20 0.38
CTSK P43235 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416027 0.87 TSHR (0.38) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL1416256 0.79 EPHX1 (0.50) FAAHEPHX1
SCHEMBL1415900 0.79 ALDH1A1 (0.37) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL1415950 0.78 EPHX1 (0.46) FAAHEPHX1
SCHEMBL452560 0.77 ZDHHC7 (0.40) FAAHMEN1KMT2AEPHX1BLM
SCHEMBL1416357 0.76 EPHX1 (0.53) EPHX1
SCHEMBL513731 0.73 EPHX1 (0.47) EPHX1
SCHEMBL127398 0.72 ALDH1A1 (0.43) FAAHMEN1KMT2AALDH1A1BLM
SCHEMBL7256336 0.72 EPHX1 (0.60) FAAHMEN1MAPK1KMT2AEPHX1
SCHEMBL22207469 0.71 EP300 (0.45) FAAHMEN1KMT2ABLMTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed