SCHEMBL1416627

SCHEMBL1416627

[CH2]CCCCCOC(=O)NC(C)C

nearest known ligand 0.53

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.43
ACHE P22303 12/20 0.42
LMNA P02545 1/20 0.36
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
NFKB1 P19838 1/20 0.36
ADRA1A P35348 1/20 0.36
RAB9A P51151 1/20 0.36
TDP1 Q9NUW8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1416029 0.92 TSHR (0.38) EPHX1ACHELMNACYP3A4TSHR
SCHEMBL1415901 0.84 TSHR (0.40) ACHELMNACYP3A4TSHRNFKB1
SCHEMBL28440301 0.83 EPHX1 (0.63) EPHX1ACHE
SCHEMBL11969614 0.81 EPHX1 (0.43) EPHX1ACHE
SCHEMBL30663333 0.81 ACHE (0.51) EPHX1ACHELMNACYP3A4TSHR
SCHEMBL7256336 0.81 EPHX1 (0.60) EPHX1ACHE
SCHEMBL23872749 0.79 EPHX1 (0.41) EPHX1ACHELMNA
SCHEMBL2536581 0.79 EPHX1 (0.68) EPHX1ACHELMNACYP3A4TSHR
SCHEMBL8382659 0.79 EPHX1 (0.52) EPHX1ACHELMNACYP3A4TSHR
SCHEMBL1416257 0.79 EPHX1 (0.68) EPHX1ACHELMNACYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2165830-B1 Lithographic printing plate precursor and printing method using the same FUJIFILM CORP (JP) 2011-03-16 EP disclosed
US-20100071574-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR AND PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2010-03-25 US disclosed
EP-2165830-A1 Lithographic printing plate precursor and printing method using the same Fujifilm Corporation (JP) 2010-03-24 EP disclosed