Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 4/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166024 | 0.84 | CHRM3 (0.39) | CHRM3NR4A2NPC1RAB9ANR4A1 | |
| Hydrochloric Acid SCHEMBL14166158 | 0.84 | NR4A2 (0.41) | CHRM3NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL14694685 | 0.83 | RXRA (0.40) | CHRM3NR4A2NR4A1NR4A3KMT2A | |
| SCHEMBL14166122 | 0.81 | CYSLTR2 (0.39) | KMT2ASMN1; SMN2ACACB | |
| SCHEMBL14694668 | 0.80 | CHRM3 (0.39) | CHRM3KMT2ASMN1; SMN2 | |
| SCHEMBL14166035 | 0.76 | RXRA (0.54) | CHRM3NR4A2NPC1RAB9ANR4A1 | |
| SCHEMBL14706758 | 0.76 | FFAR1 (0.39) | SMN1; SMN2 | |
| SCHEMBL14706780 | 0.74 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2 | |
| SCHEMBL14166117 | 0.73 | TDP1 (0.40) | — | |
| SCHEMBL14166041 | 0.71 | ACACB (0.36) | NR4A2NPC1RAB9ANR4A1NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168359-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-12-13 | — | — | WO | disclosed |