Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.65 |
| ▸ | CHRM3 | P20309 | 10/20 | 0.65 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.59 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17074633 | 0.89 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL14166020 | 0.89 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL17074632 | 0.89 | ADRB2 (0.61) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL28442824 | 0.88 | ADRB2 (0.83) | ADRB2CHRM3 | |
| SCHEMBL16205007 | 0.88 | ADRB2 (0.76) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL28435358 | 0.88 | ADRB2 (0.83) | ADRB2CHRM3 | |
| SCHEMBL14166350 | 0.88 | ADRB2 (0.76) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL16205006 | 0.88 | ADRB2 (0.76) | ADRB2CHRM3ADRB1ADRB3 | |
| SCHEMBL28435363 | 0.88 | ADRB2 (0.83) | ADRB2CHRM3 | |
| SCHEMBL14166223 | 0.87 | ADRB2 (0.74) | ADRB2CHRM3ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2718280-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | Chiesi Farmaceutici S.p.A. (IT) | 2014-04-16 | — | — | EP | disclosed |
| WO-2012168359-A1 | COMPOUNDS HAVING MUSCARINIC RECEPTOR ANTAGONIST AND BETA2 ADRENERGIC RECEPTOR AGONIST ACTIVITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-12-13 | — | — | WO | disclosed |