SCHEMBL14167341

SCHEMBL14167341

O=C(O)N1CCC(c2nc(C3=NOC(c4c(F)ccc(O)c4F)C3)cs2)CC1

nearest known ligand 0.56

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
FAAH O00519 20/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14141911 0.89 FAAH (0.54) FAAH
SCHEMBL20797285 0.89 FAAH (0.61) FAAH
SCHEMBL14167616 0.86 FAAH (0.56) FAAH
SCHEMBL19712306 0.86 FAAH (0.44) FAAH
SCHEMBL15940191 0.84 FAAH (0.55) FAAH
SCHEMBL2456051 0.83 FAAH (0.56) FAAH
SCHEMBL14141580 0.83 FAAH (0.45) FAAH
Hydrochloric Acid SCHEMBL14141881 0.83 FAAH (0.42) FAAH
SCHEMBL2455909 0.82 FAAH (0.63) FAAH
SCHEMBL30332 0.81 FAAH (0.64) FAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10004232-B2 Piperidine pyrazoles as fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2018-06-26 US disclosed
US-20140228404-A1 PIPERIDINE PYRAZOLES AS FUNGICIDES BAYER INTELLECTUAL PROPERTY GMBH (DE) 2014-08-14 US disclosed
EP-2717697-A1 ACTIVE COMPOUND COMBINATIONS Bayer Intellectual Property GmbH (DE) 2014-04-16 EP disclosed
WO-2012168188-A1 ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-12-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10004232-B2 Piperidine pyrazoles as fungicides CAT, PIR, CYP51A1 FAAH 1105/4885
US-20140228404-A1 PIPERIDINE PYRAZOLES AS FUNGICIDES CAT, PIR, PIK3C3 FAAH 1120/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.