Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.65 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.65 |
| ▸ | CNR1 | P21554 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | F7 | P08709 | 2/20 | 0.56 |
| ▸ | F3 | P13726 | 2/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | FABP3 | P05413 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6201970 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416739 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416743 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416741 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL14663391 | 1.00 | KDM4E (0.65) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416746 | 0.98 | CNR1 (0.64) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416685 | 0.98 | CNR1 (0.64) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416617 | 0.95 | CNR1 (0.64) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL1416619 | 0.95 | CNR1 (0.64) | KDM4ESOAT1CNR1ALDH1A1MAPT | |
| SCHEMBL4177624 | 0.95 | FAAH (0.61) | KDM4ESOAT1CNR1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879856-B1 | ALKYL-, ALKENYL- AND ALKYNYL CARBAMATE DERIVATIVES, THE PREPARATION AND THERAPEUTIC USE THEREOF | SANOFI AVENTIS (FR) | 2011-03-16 | — | — | EP | disclosed |