Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6452318 | 0.83 | NPC1 (0.64) | KDM4ESMN1; SMN2HPGDTDP1NPSR1 | |
| SCHEMBL6454205 | 0.82 | NR1H2 (0.56) | KDM4ESMN1; SMN2HPGDTDP1NPSR1 | |
| SCHEMBL30739004 | 0.81 | RXFP1 (0.53) | KDM4ESMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL913930 | 0.81 | RXFP1 (0.53) | KDM4ESMN1; SMN2TDP1NPC1RAB9A | |
| SCHEMBL1416558 | 0.81 | KDM1A (0.61) | KDM4EHPGDTDP1KDM1AALDH1A1 | |
| SCHEMBL16906523 | 0.80 | KDM1A (0.50) | KDM4EHPGDTDP1NPSR1KDM1A | |
| SCHEMBL21945050 | 0.80 | KDM1A (0.52) | KDM4ESMN1; SMN2HPGDTDP1NPSR1 | |
| SCHEMBL13458067 | 0.79 | DYRK1A (0.61) | SMN1; SMN2NPC1RAB9AKDM1ADYRK1A | |
| SCHEMBL12293178 | 0.79 | KDM1A (0.52) | KDM4EHPGDTDP1KDM1AALDH1A1 | |
| SCHEMBL12019038 | 0.78 | KDM1A (0.58) | KDM4ESMN1; SMN2HPGDTDP1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2306789-A1 | Phenyl-pyridine compounds | E. I. du Pont de Nemours and Company (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2306788-A1 | Iridium compounds and devices made therewith | E. I. du Pont de Nemours and Company (US) | 2011-04-06 | — | — | EP | disclosed |
| EP-2299785-A1 | Iridium compounds | E. I. du Pont de Nemours and Company (US) | 2011-03-23 | — | — | EP | disclosed |
| US-7595501-B2 | fluorinated 2-phenylpyridine compounds complexed with iridium; improved luminescence efficiency | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2009-09-29 | — | — | US | disclosed |
| US-20090206326-A1 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPRYIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | LG CHEM, LTD. (KR) | 2009-08-20 | — | — | US | disclosed |
| US-7276726-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-10-02 | — | — | US | disclosed |
| US-7199392-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylprimidines, and phenylquinolines and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-04-03 | — | — | US | disclosed |
| US-7161172-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7132681-B2 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-11-07 | — | — | US | disclosed |
| US-7129518-B2 | Electroluminescent iridium compounds with fluorinated phenylpryidines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-10-31 | — | — | US | disclosed |
| US-20040094769-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylprimidines, and phenylquinolines and devices made with such compounds | LG CHEM, LTD. (KR) | 2004-05-20 | — | — | US | disclosed |
| US-20040089867-A1 | Electroluminescent iridium compounds with fluorinated phenylpryidines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | LG CHEM, LTD. (KR) | 2004-05-13 | — | — | US | disclosed |
| US-20040075096-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | LG CHEM, LTD. (KR) | 2004-04-22 | — | — | US | disclosed |
| US-6670645-B2 | Bright, efficient, stable; increased volatility for lower temperature vacuum deposition preventing decomposition | E. I. DU PONT DE NEMOURS AND COMPANY | 2003-12-30 | — | — | US | disclosed |
| US-20030197183-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | GRUSHIN VLADIMIR (US) | 2003-10-23 | — | — | US | disclosed |
| WO-2003063555-A1 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WIHT FLUORINATED PHENYLPYRIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-07-31 | — | — | WO | disclosed |
| EP-1295514-A2 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPYRIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-03-26 | — | — | EP | disclosed |
| US-20020190250-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | LG CHEM, LTD. (KR) | 2002-12-19 | — | — | US | disclosed |
| US-20020121638-A1 | Electroluminescent iridium compounds with fluorinated phenylpyridines, phenylpyrimidines, and phenylquinolines and devices made with such compounds | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-09-05 | — | — | US | disclosed |
| WO-2002002714-A2 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPYRIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2002-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090206326-A1 | ELECTROLUMINESCENT IRIDIUM COMPOUNDS WITH FLUORINATED PHENYLPRYIDINES, PHENYLPYRIMIDINES, AND PHENYLQUINOLINES AND DEVICES MADE WITH SUCH COMPOUNDS | QDPR, DPYD, KCNQ5 | KDM4E 1379/4885SMN1; SMN2 4312/4885HPGD 1896/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.