Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | ACACA | Q13085 | 2/20 | 0.34 |
| ▸ | SUCNR1 | Q9BXA5 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13904334 | 0.93 | PDK2 (0.38) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL10064286 | 0.87 | PDK2 (0.45) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL14172965 | 0.86 | PDK2 (0.40) | PDK2L3MBTL1BCHECNR2 | |
| SCHEMBL4923313 | 0.86 | PDK2 (0.40) | PDK2L3MBTL1BCHECNR2 | |
| SCHEMBL13904290 | 0.85 | PDK2 (0.39) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL13904182 | 0.82 | PDK2 (0.38) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL13904225 | 0.81 | PTGDR2 (0.41) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL13904212 | 0.79 | PDK2 (0.33) | PDK2CA1CA2CYP3A4 | |
| SCHEMBL15125597 | 0.79 | POLB (0.46) | PDK2CA12CA1CA2CA9 | |
| SCHEMBL13904228 | 0.78 | ALDH1A1 (0.39) | PDK2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | UCL BUSINESS PLC (GB) | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139493-A1 | Bi- or Tetra-Guanidino-Biphenyl Compounds as Small Molecule Carriers | CBR3, CBR1, KCNQ3 | PDK2 4023/4885CA12 3091/4885CA1 3505/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.