⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1425925 | 0.86 | — | — | |
| SCHEMBL17258227 | 0.83 | ALDH1A1 (0.33) | — | |
| SCHEMBL16486312 | 0.69 | — | — | |
| SCHEMBL3118483 | 0.69 | — | — | |
| SCHEMBL17870593 | 0.67 | — | — | |
| SCHEMBL14843318 | 0.65 | — | — | |
| SCHEMBL1703537 | 0.61 | — | — | |
| SCHEMBL1425874 | 0.59 | — | — | |
| SCHEMBL1652805 | 0.58 | — | — | |
| SCHEMBL18613719 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3590933-B1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2021-01-06 | — | — | EP | claimed |
| EP-2638031-B9 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2020-01-08 | — | — | EP | claimed |
| EP-3124483-B1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2019-07-10 | — | — | EP | claimed |
| US-10172350-B2 | Substituted 5-hydroxy-2-phenyl-3-heteroaryl pentanenitrile derivatives, method for the production thereof and use thereof as herbicides and/or plant growth regulators | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-08 | — | — | US | claimed |
| EP-2763987-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE AS FUNGICIDALS | BAYER CROPSCIENCE AG (DE) | 2018-07-18 | — | — | EP | claimed |
| EP-3203841-B1 | SUBSTITUTED 5-HYDROXY-2-PHENYL-3-HETEROARYLPENTANONITRILE DERIVATIVES, METHOD FOR THEIR PREPARATION AND THEIR USE AS HERBICIDES AND/OR PLANT GROWTH REGULATORS | BAYER CROPSCIENCE AG (DE) | 2018-06-13 | — | — | EP | claimed |
| US-9969716-B2 | Indole derivatives as modulators of methyl modifying enzymes, compositions and uses thereof | CONSTELLATION PHARMACEUTICALS, INC. (US) | 2018-05-15 | — | — | US | claimed |
| EP-2638031-B1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | GENENTECH INC (US) | 2017-10-11 | — | — | EP | claimed |
| EP-2763993-B1 | HETEROCYCLYLPYRI(MI)DINYLPYRAZOLE | BAYER IP GMBH (DE) | 2017-04-19 | — | — | EP | claimed |
| EP-3124483-A1 | PYRAZOLE AMINOPYRIMIDINE DERIVATIVES AS LRRK2 MODULATORS | F. Hoffmann-La Roche AG (CH) | 2017-02-01 | — | — | EP | claimed |
| EP-0742202-B1 | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1999-12-01 | — | — | EP | claimed |
| CN-1143630-A | Benzophenone hydrazone derivatives as insecticides | BAYER AGROCHEM KK (JP) | 1997-02-26 | — | — | CN | claimed |
| EP-0742202-A2 | Benzophenone hydrazone derivatives as insecticides | NIHON BAYER AGROCHEM K.K. (JP) | 1996-11-13 | — | — | EP | claimed |
| US-5258270-A | A support with magenta, yellow or cyan couplers | FUJI PHOTO FILM CO., LTD. (JP) | 1993-11-02 | — | — | US | claimed |
| US-4727079-A | Brain-specific dopaminergic activity involving dihydropyridine carboxamides, dihydroquinoline and isoquinoline carboxamides | UNIVERSITY OF FLORIDA (US) | 1988-02-23 | — | — | US | claimed |
| EP-0024172-B1 | ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-11 | — | — | EP | claimed |
| EP-0003619-B1 | HETEROCYCLIC-SUBSTITUTED ANILIDE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, HERBICIDAL COMPOSITIONS CONTAINING THEM AND A METHOD OF CONTROLLING UNDESIRED PLANT GROWTH USING THEM | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1982-05-05 | — | — | EP | claimed |
| US-4317825-A | WATER SOLUBILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-02 | — | — | US | claimed |
| EP-0024172-A1 | Antitumor and immunosuppressive 4-carbamoylimidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-25 | — | — | EP | claimed |
| EP-0003619-A2 | Heterocyclic-substituted anilide derivatives, a process for their preparation, herbicidal compositions containing them and a method of controlling undesired plant growth using them | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1979-08-22 | — | — | EP | claimed |