Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Ethylenediamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.54 |
| ▸ | PDE3A known ✓ | Q14432 | 1/20 | 0.54 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | FAAH | O00519 | 1/20 | 0.65 |
| ▸ | TP53 | P04637 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.54 |
| ▸ | PPARG | P37231 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | PPARA | Q07869 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octadecanoic Acid Amide SCHEMBL179846 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Ethylenediamine SCHEMBL2096846 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL22462332 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL8852034 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL5462536 | 1.00 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL27961273 | 0.95 | SOAT1 (0.61) | SOAT1MEN1KMT2AFAAHTP53 | |
| Palmitamide SCHEMBL28284148 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL21218811 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Propylamine SCHEMBL27953558 | 0.95 | SOAT1 (0.65) | SOAT1MEN1KMT2AFAAHTP53 | |
| Octadecanoic Acid Amide SCHEMBL28709026 | 0.93 | MEN1 (0.59) | SOAT1MEN1KMT2AFAAHTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 554 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240219856-A1 | IMAGE FORMING SYSTEM AND IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2024-07-04 | — | — | US | disclosed |
| US-20240111229-A1 | IMAGE FORMING METHOD AND IMAGE FORMING APPARATUS | Konica Minolta, Inc. (JP) | 2024-04-04 | — | — | US | disclosed |
| US-11768447-B2 | Toner for developing an electrostatic charge image and an image forming method | Konica Minolta, Inc. (JP) | 2023-09-26 | — | — | US | disclosed |
| US-11687013-B2 | Toner for electrostatic charge image development, toner stored unit, image forming apparatus, and image forming method | RICOH COMPANY, LTD. (JP) | 2023-06-27 | — | — | US | disclosed |
| US-20220397837-A1 | TWO-COMPONENT DEVELOPER AND IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2022-12-15 | — | — | US | disclosed |
| US-11415904-B2 | Image forming method and image forming system | Konica Minolta, Inc. (JP) | 2022-08-16 | — | — | US | disclosed |
| US-20220057724-A1 | IMAGE FORMING METHOD AND IMAGE FORMING SYSTEM | Konica Minolta, Inc. (JP) | 2022-02-24 | — | — | US | disclosed |
| US-20220011685-A1 | TONER FOR DEVELOPING AN ELECTROSTATIC CHARGE IMAGE AND AN IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20220011687-A1 | TONER FOR DEVELOPING AN ELECTROSTATIC CHARGE IMAGE AND AN IMAGE FORMING METHOD | Konica Minolta, Inc. (JP) | 2022-01-13 | — | — | US | disclosed |
| US-20210318632-A1 | IMAGE FORMING METHOD AND IMAGE FORMING SYSTEM | Konica Minolta, Inc. (JP) | 2021-10-14 | — | — | US | disclosed |
| US-20030113648-A1 | Dry toner | RICOH COMPANY, LTD. (JP) | 2003-06-19 | — | — | US | disclosed |
| US-20030055159-A1 | Dry toner and method of preparing same | RICOH COMPANY, LTD. (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1293839-A2 | Dry toner | Ricoh Company, Ltd. (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-20030022084-A1 | Dry toner and image forming method using same | RICOH COMPANY, LTD. (JP) | 2003-01-30 | — | — | US | disclosed |
| EP-1273977-A1 | Dry toner and method of preparing same | Ricoh Company, Ltd. (JP) | 2003-01-08 | — | — | EP | disclosed |
| US-6461782-B1 | TONER, WHICH COMPRISES TONER BINDER AND COLORANT, HAVING SPECIFIED GLASS TRANSITION POINT BEFORE CURING; BINDER BEING COMPOSED OF RESIN INCLUDING CATION-POLYMERIZABLE THERMOPLASTIC RESIN HAVING PROPENYL ETHER GROUP | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 2002-10-08 | — | — | US | disclosed |
| EP-1243976-A2 | Dry toner and image forming method using same | Ricoh Company, Ltd. (JP) | 2002-09-25 | — | — | EP | disclosed |
| US-20020081510-A1 | Toner for dry developing | RICOH COMPANY, LTD. (JP) | 2002-06-27 | — | — | US | disclosed |
| EP-1205813-A1 | Toner for dry developing | Ricoh Company, Ltd. (JP) | 2002-05-15 | — | — | EP | disclosed |
| US-20020051664-A1 | Image forming apparatus, monocolor image forming apparatus, toner recycling apparatus and intermediate transfer member | RICOH COMPANY, LTD. (JP) | 2002-05-02 | — | — | US | disclosed |